In cultured glutamatergic neurons inhibitor studies have suggested the pathway indicated in Figure 5 (Palaiologos et al., 1988)
Reactive Oxygen Species (ROS) are increased by the consumption of sugars and oxidized vegetable oils, smoking, alcohol, exposure to environmental toxins, high or chronic emotional stress, circadian rhythm dysregulation (poor sleep), lack of exercise, infections, and a lack of antioxidant intake
This process takes place during, sun exposure, aging process, stress, excessive free radical production, as it happens in the scalp of individuals suffering alopecia
It notes that most trials to date, though small, have shown positive effects of creatine on major depressive and bipolar disorders, particularly when people take it alongside standard treatments
HOW TO USE :-