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Autophagy is primarily regulated through the mTOR and AMPK signaling pathways, with the former inhibiting autophagy and the latter initiating autophagy by activating the ULK1 complex (Fig

A common starting protocol is 200 g per night for the first week, with optional titration to 300 to 500 g per night as tolerated

Regulatory status: unapproved and research-use-only As of the preparation of this article, BPC-157 has not received marketing authorization from the US Food and Drug Administration, the European Medicines Agency, or equivalent national regulators for any therapeutic indication

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It decreases the lesion size of gastric ulcers induced by indomethacin (Cay-70270), aspirin (Cay-70260), or diclofenac (Cay-70680, Cay-22983) in rats at the same doses