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In a series of randomized, doubleblind trials conducted in patients stabilized on fluoxetine, saffron (Crocus sativus) significantly improved sexual function versus placebo in both men (erectile function and intercourse satisfaction) and women (arousal, lubrication, pain reduction) after 4 weeks of treatment

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The serine/threonine kinase ULK1 is a target of multiple phosphorylation events