The area covered and the technique adopted by your surgeon play a major role in the results as well as how long they last
Anyone can be affected, but some groups are more at risk: Vegetarians and vegans, since B12 mainly comes from animal products Older adults, as absorption gets harder with age People with digestive issues like Crohns or coeliac disease Those taking certain medications, such as long-term metformin or stomach acid reducers People with pernicious anaemia, an autoimmune condition that stops you from absorbing B12 If you fit into one of these categories and notice symptoms, its worth getting your levels checked
Furthermore, there are drug interactions, particularly noted among online communities like Longecity, against the concurrent use of FOXO4-DRI with certain compounds such as Rapamycin, Quercetin, corticosteroids, and cortisol, due to potential interactions that might diminish the peptide's senolytic efficacy
No one knows if there is a safe dose, or if there is any way to use this compound to treat specific medical conditions, added USADA
The Regulatory Reality: What Every Endurance Athlete Must Know The current regulatory state of play, as of early 2026: Collagen peptides are classified as food supplements in most jurisdictions, are not prohibited by WADA, and carry minimal regulatory risk for competitive athletes
