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Oral versus intramuscular administration of vitamin B12 for vitamin B12 deficiency in primary care: a pragmatic, randomised, non-inferiority clinical trial (OB12)

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Enhanced Gln metabolism not only maintains the redox state of tumor cells and decreases their sensitivity to radiation but also sustains CSCs by regulating -ketoglutaric acid (-KG)-dependent chromatin-modifying dioxygenases

since the antioxidant status of an individual varies widely, it is plausible that this can significantly influence the effect of exogenous supplementation

In a further embodiment, when slightly less viscous, or slightly more fluid auris-acceptable pharmaceutical gel formulations are desired, the biocompatible gel portion of the formulation comprises at least about 50% by weight, at least about 60% by weight, at least about 70% by weight, or even at least about 80% or 90% by weight of the compound