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Appl Microbiol Biotechnol 103:191199 Kim TH, Lee J, Kim SE, Oh DK (2021) Biocatalytic synthesis of dihydroxy fatty acids as lipid mediators from polyunsaturated fatty acids by double dioxygenation of the microbial 12 S -lipoxygenase

This TYR-catalyzed PROTAC design facilitates the in-situ cross-linking of two small molecules for targeted protein elimination, bypassing the need for prior covalent conjugation and mitigating issues of large molecular weights and unfavorable pharmacological properties of traditional PROTAC design

[ Journal Article]

Alphalipoic acid: + Hot cht c kh nng chng oxy ha mnh

Ravali Yalamanchili on 07th March 2025