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Fluorescence probes to detect lipid-derived radicals

Glutathione is produced naturally by the liver and plays an important role in building and repairing tissue

They found that microbial infections, such as SARS and H5N1 virus infections in the lungs, trigger NADPH-dependent ROS production, thereby generating oxidized phospholipids, such as oxidized 1-palmitoyl-2-arachidonoyl-sn-glycerol-3-phosphatidylcholine, to induce lung injury and cytokine production by lung macrophages via TLR4TRIF 80

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We also hypothesized abnormal tCho across multiple regions in AnxDs, implicating widespread neurometabolic changes in these disorders