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Arch Dis Child Fetal Neonatal Ed

Saturday 9 a.m

Application is typically once or twice daily to the target area

Results: We included 1263 patients, 953 (75%) attended by mICU and 310 (25%) by RRV

Enlargement of the ring system of 23 , by oxidatative cyclization of Hcy 1 /Hcy 3 side chains rather than the Hcy 1 /Cys 3 side chains of 23 resulted in a compound comprising a 14-membered macrocycle but with a somewhat lower affinity to IRAP (Ki = 5.1 nM), vide infra