Due to its properties, as an antioxidant, Glutathione can significantly and immediately reduce the damage caused by reactive oxygen
Cysteine plays a role in the sulfation cycle, acting as a sulfur donor in phase II detoxification and as a methyl donor in the conversion of homocysteine to methionine [13-15]
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Furthermore, formononetin alleviated DA depletion and reduced ACh levels, indicating its protective effect on dopaminergic neurons
As glutathione can improve the numbers and activity of macrophages, peptic ulcers may be exacerbated [40] Increased susceptibility to melanoma: Theoretically, long-term administration of systemic glutathione switches eumelanin to pheomelanin, and may increase the susceptibility towards development of melanoma in the long run.[28] Figure:2 ROLE OF GLUTATHIONE IN SKIN DISORDERS OTHER THAN HYPERPIGMENTATION : A decrease in the cellular and serum levels of glutathione has been speculated to be associated with the pathogenesis of autoimmune and inflammatory dermatoses that include psoriasis, vitiligo, alopecia areata, polymorphic light eruption, acne vulgaris, etc