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The increase of intracellular ROS is believed to correlate with the activation of nuclear factor (NF)-kappa B, a transcription activator linked to the elaboration of several cytokines (Figure 6)

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The peptide's effects on memory consolidation appear mediated through enhanced hippocampal long-term potentiation (LTP), the neurophysiological basis of memory storage, with Dihexa treatment increasing both the magnitude and persistence of synaptic strengthening

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