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In the 2024 WADA Prohibited List (World Anti-Doping Agency, 2024c) Section 4: hormone and metabolic modulators, AIs (Subsection S4.1) and anti-estrogenic substances, including anti-estrogens and SERMs (Subsection S4.2), are prohibited at all times (in- and out-of-competition)

Stack the two gaps together and the picture for the conventional protocol is unflattering: approximately one-fifteenth of the studied dose, delivered by a route that animal data suggest requires several-fold more peptide, targeting a compound whose dose-response may not be monotonic anyway

doi:10.3390/nu2030299

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