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2011 Sep;94(3):847-53

People at Risk The risk of adverse effects is especially high in people with [70+]: Digestive conditions (Crohns disease, ulcerative colitis, diverticulitis) A history of bowel surgery Severe hemorrhoids Kidney, heart, and liver disease Allergy to coffee The FDA only approves colon cleansing to prepare for medical procedures and has issued several letters warning about unapproved uses

The practical result is that IGF-1 elevation is more stable week to week on CJC-1295 than on sermorelin

Ganti S, Taylor SL, Kim K, Hoppel CL, Guo L, Yang J, et al