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Leptospirosis Leptospira spp., a family of helical spirochetes, cause the dreaded zoonotic disease, leptospirosis which can manifest acutely with multiorgan dysfunction and acute kidney injury, and asymptomatic patients might progress to chronic tubulointerstitial nephritis even resulting in endstage kidney disease

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The compound when taken orally as a sweetener caused liver failure

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Zudem wird bei der industriellen Lebensmittelverarbeitung und Konservierung (Ausnahme: Tiefkhlung) Glutathion weitgehend zerstrt