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The copper ion is coordinated to the peptide through the nitrogen atoms of the glycine and histidine residues, giving the compound its distinctive blue color in crystalline form

Vitale G., Salvioli S., and Franceschi C., Oxidative Stress and the Ageing Endocrine System, Nature Reviews Endocrinology 9, no

Animal models showed that these characteristics can induce ASD-associated behavior, suggesting an intimate relationship between the microbiota, gut, immune system and the brain in ASD

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Pearson et al., 2021), and this may also apply for the semisynthetic variants