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Pamela Frank, BSc(Hons), ND Dr

Annu Rev Pathol Mech Dis

Similar mechanismssuch as SLC7A11/GPX4 inhibition, ferritinophagy, and Nrf2 suppressionare established ferroptosis pathways in HCC, supporting the biological plausibility of the ESC findings (An et al

Current research has moved beyond demonstrating the efficacy of single strains and now focuses on designing multimodal, precision interventions, marking a shift from discovery to design