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as levels normalise, improved daytime energy may temporarily affect sleep-wake cycles Individual sensitivity : A small subset of people may be more sensitive to changes in B vitamin levels Formulation factors : Some B12 supplements contain additional ingredients that could affect sleepalways check product labels for stimulants like caffeine For the vast majority of people, vitamin B12 supplementation does not cause sleep disturbances when taken as directed
What the clinical trials show The short answer is no
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The British Society for Haematology emphasises that treatment should not be delayed whilst awaiting confirmatory test results if clinical suspicion of B12 deficiency is high, particularly when neurological symptoms are present