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Effects on neurotransmitter systems may support the mood, cognitive, and sleep dysregulation that are near-universal in long COVID

doi: 10.1182/blood-2004-03-0920

Testosterone cypionate is a long-acting ester formulation typically dosed every 1-4 weeks depending on patient response and prescriber protocol

These modifications were designed to reduce binding affinity for IGF binding proteins (IGFBPs), which normally sequester circulating IGF-1 and limit its bioavailability