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Conclusions Arterial lactate, pH, BMI, and NE duration and dose were associated with AVP responsiveness and shock duration during septic shock, and rebound hypotension occurred in 9% during recovery

Ferre, G

Expert Opinion on Biological Therapy

Ohta, M

Currently, most studies concentrate on the impact of APP on the intracellular redox state, including the APP generated reactive species on cellular oxidative stress, leading to lipid peroxidation, DNA damage, mitochondrial dysfunction, and apoptosis 18