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And just like that, the designer in me evolved into a formulator

However, some molecules or drugs, such as erastin, sulfasalazine, sorafenib, and RSL3, are able to block glutathione synthesis or devitalize GPX4

A., Liu, E

hordei (Dudler et al., GstA1 gene, which encodes a 29 kD GST protein (GST29) was specifically inducible by fungal infections and exogenous GSH, but not by various xenobiotics that typically induce GST activity (paraquat, atrazine, alachlor, metolachlor) (Mauch and Dudler, GstA1 increased dramatically within 2 h after infection with barley or wheat powdery mildew

The cellular functions of GSTO1 have not been fully elucidated, although a role in cellular stress responses is emerging 8,9,10