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Description & Pharmacodynamics Epithalon is derived from epithalamin, a natural peptide produced in the pineal gland
systematically compared the transduction distribution of AAV1, 2, 5 and 8 serotypes in the knee joints of mice and found that different AAV serotypes showed different tissue tropisms in tissues such as synovium, cartilage and subsynovial bone (181)
Another example is CGA-N12, a synthetic antimicrobial peptide that exerts potent antifungal effects against Candida albicans by inducing reactive oxygen species (ROS) accumulation and collapsing the mitochondrial membrane potential, ultimately triggering apoptosis (Li et al., 2018)
PLoS One 12 , e0171781 (2017)