DMSA has been known to be an effective heavy metal chelator since the 1950s and has been extensively studied since then beginning in the Peoples Republic of China, Japan, and Russia and then eventually in Europe and the USA
This observation lacks rigorous controlled trial data but appears consistently in user reports
Ingredients Aqua (Water), Paraffinum Liquidum (Mineral Oil), Cetearyl Alcohol, Petrolatum, Synthetic Wax, Polysorbate 60, Glycerin, Sorbitan Stearate, Dimethicone, Caprylic/Capric Triglyceride, Glutathione, Ascorbyl Tetraisopalmitate, Diacetyl Boldine, PEG-40 Hydrogenated Castor Oil, Sodium Levulinate, PPG-8-Ceteth-20, PPG-4-Ceteth-20, Butylene Glycol, Glyceryl Stearate, PEG-100 Stearate, Palmitic Acid, Stearic Acid, Levulinic Acid, Carbomer, Xanthan Gum, Disodium EDTA, Tocopherol, Triethanolamine, Citric Acid, Sodium Citrate, Sodium Benzoate, Sodium Metabisulfite, Methylparaben, Parfum (Fragrance), Benzyl Alcohol
Leishmania lipophosphoglycan (LPG) interacts with mitochondrial membranes, reducing mitochondrial membrane potential and impairing ROS production (Rodrigues et al., 2025)
Creatine supplementation reduces depressive symptoms, particularly when combined with selective serotonin reuptake inhibitors, and may improve brain energy metabolism and neuroplasticity