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A matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) assay revealed several proteins with antioxidant functions including a GST that were differentially expressed between compatible and incompatible interactions, indicating the differential accumulation of ROS in infected tissues (Li et al., Hemibiotrophic Fungi The important role of GSTs in antifungal plant resistance was demonstrated also in hemibiotrophic plant-fungus interactions

Actual lightening effects typically become noticeable after 8-12 weeks of consistent use

Toxicol Res Appl 4:4751 Hemachand T, Shaha C (2003) Functional role of sperm surface glutathione S-transferases and extracellular glutathione in the haploid spermatozoa under oxidative stress

Histopathological analysis further revealed that high expression of GSTA1 in mouse livers (Figure 4F, GSTA1) reduced steatosis, hepatocellular ballooning, and lobular inflammation, which was confirmed by the decreased NAS score (Figure 4F)