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Kulai, MD Fellow in Transplant Hepatology, Mayo Clinic School of Graduate Medical Education, Mayo Clinic College of Medicine and Science, Rochester, Minnesota

I now give myself B12 shots weekly and I would never have guessed how easy and pain-free they are

Weekly injections in this phase are important for: Keeping B12 stores full Watching how the patient responds and adjusting as needed Starting to move to less frequent injections Maintenance Phase: Monthly Injections After the first two phases, maintenance therapy starts with monthly injections

Some studies employ a loading regimen of higher initial doses followed by lower maintenance doses

Any unusual symptoms that affect daily life