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Two major pathways dominate

This synthetic vitamin B12 is the same type found in fortified cereals, so you may have ingested man-made vitamin B12 in your life already

For purines synthesis, the base is synthesized and attached to the sugar, while for pyrimidine synthesis, the sugar group is added after the base is produced

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Proc Natl Acad Sci U S A 106(6):19711976 De Groot NS, Pallars I, Avils FX, Vendrell J, Ventura S (2005) Prediction of hot spots of aggregation in disease-linked polypeptides