Even though there are great resemblances between XO and AO functions, for example, both enzymes enable oxidation as well as reduction reactions across a broad spectrum of substrates, with oxidation reactions being significantly more prevalent [45], significant differences also exist
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Despite the redundancy accorded to this system by the continued production of JNK2, it appears reasonable to conclude that the JNK1 signaling pathway may be playing a role in T-cell receptor initiated Th cell proliferation, differentiation or apoptosis
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