Preclinical animal studies further validate its neuroprotective potential: phillyrin A improves learning and memory in senescence-accelerated mice, activates the Nrf2 signaling pathway in APP/PS1 mice, upregulates antioxidant proteins (NQO1, GPX4), and normalizes cerebral iron content through modulation of TFRC, DMT1, FTH, and FTL gene expression (234)
RNA and EGF accelerate cell regeneration and skin repair
*Correspondence: Do-Hee Kim, [email protected] This article was submitted to Cancer Metabolism, a section of the journal Frontiers in Oncology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
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The authors also acknowledge financial support from UGC-CAS doctoral fellowship (to P.P.), DST-INSPIRE fellowship (to O.M.) and CSIR-Junior research fellowship (to A.B.)