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Long-term studies in laboratory models suggest that sustained NNMT inhibition may reprogram cellular metabolism toward enhanced oxidative capacity and improved stress resistance

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In other words, pills can take longer to raise B12 levels, so if you need a quick boost, injections are the better choice

Liraglutide has longer safety data and does not appear to cause b12 issues in clinical practice

While no standardized protocol exists, many clinicians assess patients once their post-surgical weight loss has stabilized, often 6-12 months after surgery, though timing should be individualized based on clinical response and metabolic needs