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[113] had seizures by 10 months of age, progressive clinical course, and two died at 19 months and 10 years

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However, formulators should avoid high concentrations of chelating agents such as EDTA, as they may interfere with copper binding

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In particular, [1- 13 C]DHA, a 13 C enriched version of dehydroascorbic acid, has been studied with hyperpolarized (HP) 13 C magnetic resonance (MR) in preclinical models of cancer, diabetes, acute kidney injury, and fatty liver disease 15,16,17,18,19,20