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In a Phase II clinical trial targeting patients with obesity, Danuglipron showcased significant weight loss effects over a 32-week treatment period

The short-term gains are not worth the long-term damages

The Centers for Disease Control and Prevention (CDC) recommends setting a weekly weight loss target of reducing your daily calorie intake by 500 calories eatinga balanced diet of whole grains, lean proteins, low fat dairy, fruits, and vegetables limiting added sugars, sodium, saturated and trans fats, and alcohol getting at least 150 minutesweekly of moderate intensity aerobic exercise strength training for at least 2 days weekly sleeping for 7 to 9 hourseach night regularly checking in with a doctor, personal trainer, or registered dietitian Learn more about how to lose weight sustainably

However, prescribers must be aware that the FDA issued a safety alert in April 2025 specifically addressing compounded topical finasteride

Jul 22 2020;21(15)doi:10.3390/ijms21155175