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Subsequent oxidative stress results in the age-dependent peroxidation of proteins, lipids, and nucleic acids by intracellular mitochondria, destruction of the mitochondrial membrane permeability, and reduction of oxygen respiratory chain activity, leading to an increase in the number of active oxygen species (Oveland et al., 2012

The procedure is quick, minimally uncomfortable, and requires no recovery time

Organisms possess intricate regulatory mechanisms to ensure the selective degradation of proteins, thereby maintaining protein homeostasis

Both our sensitivity analyses and the application of alternative filtering thresholds yielded consistent results, supporting the stability of our findings

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