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Sen Gupta P, et al (2024) Vitamin E alleviates chlorpyrifos induced glutathione depletion, lipid peroxidation and iron accumulation to inhibit ferroptosis in hepatocytes and mitigate toxicity in zebrafish

GSH, a classic non-enzymatic antioxidant, directly scavenges ROS, and the GSH/GSSG ratio is a key indicator of cellular redox status [120]

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Currently, 8 GPxs (GPx1GPx8) have been identified in mammalian tissues, which exhibit the genetic, structural and dynamic differences and perform common and separate functions [12] (Fig