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In the 12-week randomised controlled trial documented in the obesity pharmacotherapy literature, the 1 mg/day group achieved statistically meaningful separation from placebo

Here we determined the mechanisms and rate constants for the glutathione/glutaredoxin-dependent redox reactions of the widely used redox probe roGFP2 and addressed the question of how mono- and dithiol glutaredoxins catalyze the reduction of roGFP2(S 2 ) as a model non-glutathione protein disulfide substrate