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Because free radicals can damage skin structure, reducing that damage supports smoother looking skin

For people with MTHFR variants, supplementing with the active form is often what makes the difference between methylation working and methylation falling short

This work was published in Nature Medicine (2009)

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These users describe skin quality remaining noticeably superior to pre-treatment baseline even year post-discontinuation, with specific improvements including reduced fine lines maintaining 50-70% of treatment peak reduction, improved skin firmness and elasticity sustaining 40-60% of maximum improvement, better overall texture and appearance persisting at 50-80% of treatment levels, and completely resolved specific issues like scarring or hyperpigmentation staying improved