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Exploration of pharmacological interventions to prevent isoproterenol-induced myocardial infarction in experimental models

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Replacement of Q residues with N residues at the polyamination sites had no impact on GSH binding affinity or GST enzymatic activity compared to that of wild-type GST

Instead of viewing vitamin B12 solely as a nutrient whose deficiency causes anemia or nerve damage, researchers now believe it also plays an important role in cellular energy production, muscle maintenance and healthy brain aging

As predicted in silico, the addition of relatively small, lipophilic groups to the meta position of the ring maintained or slightly improved affinity when measured by the R2KD assay (Table 2)