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Grantham-McGregor S, Cheung YB, Cueto S, et al

Metformin attenuates experimental autoimmune arthritis through reciprocal regulation of Th17/Treg balance and osteoclastogenesis

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Existing reviews tend to fall into two categories: overly broad analyses that emphasize reactive oxygen species (ROS) biology without sufficiently addressing GSH, or highly focused discussions on chemical linkers that overlook translational relevance

Hence, augmentation of autophagy function in acute seizure and SE could be a compensatory mechanism to restrict neuronal loss and promote rearrangement of neurons and synaptic instability