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Retrieved 20 May 2024

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Severe allergic reactionssuch as difficulty breathing, rash, or swelling of the face and throatare extremely rare but require immediate medical attention

Some researchers believe that GIP receptor activation partially offsets the nausea caused by GLP-1 stimulation, which could explain why some patients tolerate tirzepatide better than pure GLP-1 agonists despite receiving more potent appetite suppression