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However, as reperfusion time extended, ACSL4, iron, and malondialdehyde levels increased, while GPX4 levels decreased, suggesting that ferroptosis predominantly occurs during the reperfusion phase rather than the ischemic phase

Indian J Dermatol 2018

It helps protect liver cells from oxidative stress

AMPK can directly or indirectly affect the activity and expression of multiple transcription factors, including members of the peroxisome proliferator-activated receptor (PPAR) family [66]