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Thus, while astrocytes appear to occupy a key intersection between iron metabolism and neuroinflammation in AD, conclusive evidence establishing ferroptosis as a primary pathogenic driver in human disease is still lacking

The choice depends on whether metabolic enhancement or appetite control is the primary need

Zhao M, Wang X, He M, Qin X, Tang G, Huo Y, Li J, Fu J, Huang X, Cheng X, et al

Data availability statement The raw data supporting the conclusions of this article will be made available by the authors, without undue reservation

However, not all interventions proved effective, as acetyl-L-carnitine plus alpha-lipoic acid failed to reverse insulin resistance in another NAFLD mouse model (32)