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This is consistent with GHK-Cus known role in upregulating collagen synthesis in dermal fibroblasts, a mechanism confirmed in a comprehensive review in Biomolecules documenting GHK-Cus influence across more than 4,000 human genes involved in tissue remodeling and repair

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In vitro studies using microarray and transcriptomic analyses on various cell lines have demonstrated that GHK-Cu can modulate the expression of a substantial portion of the human genome

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