There are some very rare side effects listed in medical literature (mostly when large doses are given): for example, one out of many thousands of patients might develop a disturbance in liver enzymes or a tingling in the fingers or toes
This enzymatic overactivity is strongly associated with obesity, insulin resistance, and metabolic syndrome
Vitamin B12 shots are usually safe, but knowing about possible side effects and problems is key for good care
Standard initial treatment for patients: Without neurological involvement: 1000 g intramuscularly three times a week for two weeks
[2,6,7] Although it has historically been positioned as a salvage therapy, IT therapy is now being considered earlier in the treatment spectrum. Most IT pumps are placed for failed back surgery syndrome, but they are indicated for other types of cancer or noncancer pain as well