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Patients in the treated group received 300 mg of ALA three times daily (900 mg/day) while those in the control group received a placebo

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In MS, GSH metabolism is impaired in regions of the CNS that have been demyelinated and correlates with mitochondrial dysfunction and axonal injury ( 2 Mechanisms of redox regulation in the CNS 2.1 GSH as an antioxidant in the brain The brain, being one of the most metabolically active organs in the body, requires a large share of oxygen relative to its mass

The oxidised forms of NAD + and NADP + were found at higher concentrations than the reduced forms in samples from all C

Vitamin B12 is a water-soluble vitamin required for red blood cell production, DNA synthesis, and neurologic function