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It has been demonstrated in a MC908 mouse model that coupling of LTC4 with its receptor CysLT2R, which is expressed in mice and in humans in a population of peripheral sensory neurons, represents a potent itch inducer [55, 56]

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Unlike fat-soluble vitamins (A, D, E, and K), which are stored in fat tissue for long periods, water-soluble vitamins are processed relatively quickly: your body takes what it needs, stores a small amount in the liver, and passes most of the rest in urine