216 Epigenetic rewiring Epigenetic rewiring refers to the transformation of heritable gene expression regulation patterns without altering the DNA sequence, comprising transcription factor regulation, histone modification, and RNA epigenetic modification
Some medications are only a problem at certain dosages or intervals.[ref] Primaquine, an anti-malaria drug, is linked to a dose-dependent risk of hemolytic anemia in people with G6PD deficiency.[ref] Other drugs that cause Predictable or Possible hemolysis include:[ref] Drugs that cause predictable hemolysis: Dapsone Primaquine Methylene Blue Cotrimoxazole Sulfadiazine Quinolones (ciprofloxacin, ofloxacin, nalidixic acid) Nitrofurantoin Rasburicase Toluidine blue Drugs causing possible hemolysis: Chloroquine Quinine high dose aspirin, acetaminophen Sulfasalazine Chloramphenicol Isoniazid Ascorbic acid (very high doses[ref]) Glibenclamide Vitamin K Isosorbide Dinitrate What about hydroxychloroquine
However, the application is limited by the scarcity of donor tissue, additional trauma to the patient and surgical complications (Hao et al., 2022
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