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In the laboratory, researchers study BPC-157 in cell-culture and preclinical models to investigate processes associated with tissue repair, fibroblast behavior, collagen organization, and angiogenesis-related signaling, including pathways linked to vascular endothelial growth factor (VEGF) and nitric-oxide systems

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BPC-157 may restore healing capacity in individuals who have used NSAIDs extensively, though avoiding NSAIDs during peptide therapy remains preferable when possible