A., Xin, G., Li, Z., Yang, J., Lane, A
In addition, there was upregulation in the expression of the proinflammatory cytokine Tnf and genes involved in the integrated stress response ( Atf3 , Atf5 , Ddit3 and Dele1 ) and reduced expression of the adipokine Adipoq
University of California, Davis, Department of Nutrition
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Notwithstanding, since the mitochondrial membrane is impermeable to acyl-CoA, to enter the mitochondria, fatty acids must resort to a specific enzymatic mechanism that uses L-Carnitine as a carrier molecule [28]