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While huntingtin folds and functions normally, the mutant form exhibits aberrant folding, leading to aggregation and neuronal toxicity

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Circulatory symptoms You might notice breathlessness even while sitting still, a rapid heartbeat, or unusually pale skin

In this regard, other studies have indicated that the amount of oxidative stress increases during the blood storage, and one of the markers, which has been increased, is the amount of carbonylation membrane proteins of the RBCs

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