A further animal study from 2016 confirmed immunomodulatory effects
Wiernicki B, Maschalidi S, Pinney J, Adjemian S, Vanden Berghe T, Ravichandran KS, Vandenabeele P
De Leo E, Elmonem MA, Berlingerio SP, Berquez M, Festa BP, Raso R, Bellomo F, Starborg T, Janssen MJ, Abbaszadeh Z, Cairoli S, Goffredo BM, Masereeuw R, Devuyst O, Lowe M, Levtchenko E, Luciani A, Emma F, Rega LR (2020) Cell-based phenotypic drug screening identifies luteolin as candidate therapeutic for nephropathic cystinosis
Shape similarity screening is widely used in early drug development to discover novel chemical scaffolds and to optimize the potency and pharmacokinetic properties of the lead compounds ( in vitro drug susceptibility assay
Front Aging Neurosci 11:435469