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Although BPC 157 has shown promising results in preclinical studies, further research and clinical trials need to be done in order to determine its potential therapeutic application and safety in humans

No significant difference in the prevalence of symptoms was found between participants with MMA levels 400 nmol/l (n = 60) and those whose levels were 600 nmol/l showed some improvement in neurological symptoms (Hvas, 2001b)

2020;77:66980.e4

IET Nanobiotechnology (2025)

Given the high frequency of musculoskeletal problems in individuals with clEDS (Supplementary Table 1), we propose that coordination of care and follow-up for patients with clEDS lie with (pediatric) rheumatology and if available with specialized EhlersDanlos services