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For instance, quercetin and luteolin at higher concentrations promote apoptosis and reduce proliferation in melanoma cells by generating ROS, thus potentially inhibiting tumor progression 138,147,148

That would sound like a moderate strain

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Ferroptosis in the colon epithelial cells as a therapeutic target for ulcerative colitis

Circulation 102:E73-86 Chibaudel B et al (2020) Association of bevacizumab plus oxaliplatin-based chemotherapy with disease-free survival and overall survival in patients with stage II colon cancer: a secondary analysis of the AVANT trial