This temporary effect is probably due to immune system activation, mediated by cytokines that interfere with the hypothalamo-pituitary-ovarian (HPO) axis
If your protocol requires taking them at the same time, you can safely draw them into the same syringe right before injecting, but they must never live in the same storage vial
[It] also aids in DNA synthesis and is involved in the metabolism of carbohydrates, fats, and proteins." Because it's so important, those with this type of vitamin deficiency, which is diagnosed via a blood test, are usually recommended to take either supplements or get regular B12 shots
If you consistently react poorly to methylated nutrients, consider switching to Hydroxo B12 with Folinic Acid, which provides methyl-free forms of B12 and folate that your body converts to methylated forms more gradually, allowing for gentler methylation support without forcing the process Never take Methyl B12 with L-Methylfolate within 5 hours of bedtime as it can interfere with sleep
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